Studying Trends of Auto-Regulation in Severe Head Injury in Paediatrics

CompletedOBSERVATIONAL
Enrollment

135

Participants

Timeline

Start Date

July 1, 2018

Primary Completion Date

April 30, 2024

Study Completion Date

March 31, 2025

Conditions
TBI (Traumatic Brain Injury)
Interventions
OTHER

Data Collection

This is an observational prospective cohort study. Children admitted to ten identified PICUs in the UK with severe TBI with a clinical need for ICP and ABP monitoring will be included for data collection. The database will contain routinely monitored physiological parameters during management of PTBI in PICU. Without disturbing the routine care and management of these patients, investigators aim to collect this data continuously in a bedside laptop equipped with the study software (ICM+, Cambridge Enterprise Ltd, Cambridge, UK). Alongside these physiological parameters, investigators will also collect relevant clinical and demographic data (details below) and follow these patients for up to 12 months post ictus to assess neuro-psychological outcome.

Trial Locations (1)

CB2 0QQ

Shruti Agrawal, Cambridge

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Action Medical Research

OTHER

lead

Shruti Agrawal

OTHER

NCT05688462 - Studying Trends of Auto-Regulation in Severe Head Injury in Paediatrics | Biotech Hunter | Biotech Hunter