Enhancing Exercise and Psychotherapy to Treat Pain and Addiction in Adults With an Opioid Use Disorder (EXPO; R33 Phase)

NARecruitingINTERVENTIONAL
Enrollment

198

Participants

Timeline

Start Date

February 10, 2023

Primary Completion Date

November 30, 2026

Study Completion Date

November 30, 2026

Conditions
Opioid Use DisorderPain
Interventions
OTHER

Exercise

"Participants who are randomized to exercise will be perform exercise on stationary bikes. Participants randomized to Voluntary Exercise will exercise on a standard stationary bike where they will pedal at their voluntary rates. Participants randomized to Assisted Exercise will exercise on a special bike that assists them to pedal faster than they do voluntarily on their own (assisted (exercise) bike)."

BEHAVIORAL

Psychotherapy Pain and Addiction (I-STOP)

"Participants who are randomized to receive I-STOP will receive the Self-regulation Treatment for Opioid addiction and Pain (STOP) program modified for inpatients/residential drug treatment (I-STOP). I-STOP uses empirically validated pain psychotherapy approaches targeted to patients with an OUD using psycho-physiological self-regulation components and biofeedback with Bio-dots."

Trial Locations (2)

44106

RECRUITING

Case Western Reserve University, Cleveland

80217

NOT_YET_RECRUITING

University of Colorado at Denver, Denver

All Listed Sponsors
collaborator

University of Colorado, Denver

OTHER

collaborator

National Center for Complementary and Integrative Health (NCCIH)

NIH

collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

lead

Case Western Reserve University

OTHER