HER2 Targeted HypoSti.CAR-T Cells in HER2 Positive Advanced Solid Tumors

Dose escalation: dose -1 (1×10\^6 cells/kg) ,dose 1 (3×10\^6 cells/kg) , dose 2 (6×10\^6 cells/kg), dose 3 (1×10\^7 cells/kg), dose 4 (1.5×10\^7 cells/kg). Dose expansion: RP2D

Administered intravenously at dose of 100-200mg/m2 on day -5

Administered intravenously at a total dose of 15-30mg/kg on day -3 and day-2

Administered intravenously at dose of 30mg/m2/d on day -3 and day -2 only in the first infusion of HypoSti.CAR-HER2 T cells