Pazopanib With or Without Pembrolizumab for Metastatic Soft Tissue Sarcoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

116

Participants

Timeline

Start Date

March 1, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Soft Tissue Sarcoma
Interventions
DRUG

pembrolizumab, pazopanib

Pembrolizumab will be given for a maximum of 2 years i.e. a total of 35 cycles of pembrolizumab with the q3 week dosing. Participants who complete study intervention after 2 years of pembrolizumab can be treated with pazopanib monotherapy based on physician's judgement. The duration of optional pembrolizumab crossover treatment will be maximum of 2 years i.e. a total of 35 cycles of pembrolizumab for patients progressing on pazopanib.

Trial Locations (1)

03722

RECRUITING

Severance Hospital, Seoul

All Listed Sponsors
lead

Yonsei University

OTHER