Managing Fear of Cancer Progression Metacognition-based Vs Supportive-expressive Based Approaches

NARecruitingINTERVENTIONAL
Enrollment

261

Participants

Timeline

Start Date

December 20, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

June 30, 2026

Conditions
Advanced or Metastatic CancerFear of Cancer ProgressionMetacognition-based InterventionSupportive-expressive Based InterventionPsychooncology
Interventions
BEHAVIORAL

ConquerFear intervention

ConquerFear is a manualized intervention, consists of six individual sessions over 10 weeks. The key goals of this intervention are the following: (1) teach strategies for controlling worry and excessive threat monitoring, (2) modify underlying unhelpful beliefs about worry, (3) develop appropriate monitoring and screening behaviours, (4) encourage acceptance of the uncertainty brought about by a cancer diagnosis, and (5) clarify values and encourage engagement in values-based goal setting (19). Each session will last 60-90 minutes and be delivered by a trained therapist. After each session, participants will be given home-based exercises to practice the skills learned in the sessions. With the uncertainty surrounding the COVID-19 pandemic, instead of face-to-face sessions only, a hybrid mode of intervention delivery will be used by offering participants the choice of face-to-face or online sessions.

BEHAVIORAL

CALM intervention

CALM is a semi-structured, manualized, individual psychotherapy intervention designed for patients with advanced cancer. It includes 3-6 individual therapy sessions, with each approximately lasts 45-60 minutes, delivered over 3-6 months. The sessions cover 4 domains: 1) symptom management and communication with health care providers; 2) changes in self and relations with close others; 3) sense of meaning and purpose; and 4) the future and mortality. All modules will be addressed with each patient, but the sequencing and time devoted to each domain can be varied, based on the concerns that are most relevant to each patient.

BEHAVIORAL

Basic Cancer Care

Basic Cancer Care intervention for the control arm was developed to help cancer survivors with health maintenance in long-term through providing comprehensive lifestyle guidance. The intervention incorporates relaxation training, dietary and physical fitness consultations with the key goals to (1) teach relaxation techniques, (2) offer personalized diet and physical activity advice, and (3) enhance survivors' perceived control over illness, thereby leading to better adjustment to cancer. Similar to the ConquerFear intervention, Basic Cancer Care intervention consists of 6 individual sessions over 10 weeks. Each session will last 60-90 minutes and be delivered by a trained therapist, a registered dietitian, and an exercise physiologist, respectively. A hybrid mode of intervention delivery will be also used by offering participants the choice of face-to-face or online sessions.

Trial Locations (4)

Unknown

RECRUITING

Queen Mary Hospital-Department of Obstetrics & Gynaecology, Hong Kong

NOT_YET_RECRUITING

Queen Mary Hospital-Department of Oncology, Hong Kong

RECRUITING

Queen Mary Hospital-Department of Surgery, Hong Kong

NOT_YET_RECRUITING

Tung Wah Hospital-Department of Surgery, Hong Kong

All Listed Sponsors
collaborator

Research Grants Council, Hong Kong

OTHER

lead

The University of Hong Kong

OTHER