A Study of Photobiomodulation (PBM) Therapy in People With Oral Graft-Versus-Host Disease (GVHD) After Stem Cell Transplant

PHASE2RecruitingINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

December 22, 2022

Primary Completion Date

December 22, 2026

Study Completion Date

December 22, 2026

Conditions
Graft-Versus-Host DiseaseGVHDUndefined
Interventions
DEVICE

Photobiomodulation Therapy

Participants with a history of allo-HCT and diagnosis with oral chronic GvHD randomized to the treatment arm will be treated with oral photobiomodulation/PBM (via Thor LX2.3 system device) for 28 days

OTHER

Placebo sham device

Participants with a history of allo-HCT and diagnosis with oral chronic GvHD randomized to the placebo arm will be treated with a placebo sham device (via Thor LX2.3 sham device setting) for 28 days

Trial Locations (9)

10065

RECRUITING

Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York

10604

RECRUITING

Memorial Sloan Kettering Westchester (Consent only), Harrison

11553

RECRUITING

Memorial Sloan Kettering Cancer Center @ Nassau (Consent only), Uniondale

11725

RECRUITING

Memorial Sloan Kettering Cancer Center @ Commack (Consent only), Commack

15213

RECRUITING

University of Pittsburgh Medical Center (Data Collection Only), Pittsburgh

20892

RECRUITING

National Institute of Health (Data Collection AND Specimen Analysis), Bethesda

07920

RECRUITING

Memorial Sloan Kettering at Basking Ridge (Consent only), Basking Ridge

07748

RECRUITING

Memorial Sloan Kettering Monmouth (Consent only), Middletown

07645

RECRUITING

Memorial Sloan Kettering Cancer Center @ Bergen (Consent only), Montvale

All Listed Sponsors
lead

Memorial Sloan Kettering Cancer Center

OTHER