Bring BPaL2Me Trial Comparing Nurse-Led RR-TB Treatment to Physician-Led RR-TB Treatment

NARecruitingINTERVENTIONAL
Enrollment

2,944

Participants

Timeline

Start Date

September 4, 2023

Primary Completion Date

June 30, 2028

Study Completion Date

December 31, 2030

Conditions
Drug Resistant Tuberculosis
Interventions
OTHER

Nurse-Led Treatment in Primary Care

At a primary care clinic intervention site, a nurse will be available once or twice weekly. The days/times will be dependent on clinic volume (i.e., cluster size), with scheduled rotations between PCCs. This rotation between PCC sites will mimic the physician's responsibilities/availability at a district hospital and creates parity between the trial arms. In this trial, we will have nurses dedicated to the management of RR-TB treatment, yet the volume at each site will not require the presence of a full-time nurse.

Trial Locations (5)

3201

RECRUITING

Doris Goodwin Hospital, Pietermaritzburg

7007

RECRUITING

Murchison Hospital, Port Shepstone

Unknown

RECRUITING

King Dinuzulu TB Hospital, East London

RECRUITING

Nkquebela TB Hospital, East London

RECRUITING

Jose Pearson Hospital, Port Elizabeth

All Listed Sponsors
collaborator

University of Witwatersrand, South Africa

OTHER

collaborator

University of Cape Town

OTHER

collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

lead

Johns Hopkins University

OTHER

NCT05671718 - Bring BPaL2Me Trial Comparing Nurse-Led RR-TB Treatment to Physician-Led RR-TB Treatment | Biotech Hunter | Biotech Hunter