40
Participants
Start Date
June 1, 2023
Primary Completion Date
December 31, 2025
Study Completion Date
June 30, 2026
disulfiram and cisplatin
on the first day of treatment, patients were given intravenous drip of 80mg/m2 cisplatin, and 21 days was a course of treatment, lasting for 6 courses. Take 400mg disulfiram orally every day, and continue to use it until the end of chemotherapy. According to the patient's tolerance to disulfiram, the dose of disulfiram can be re-evaluated during the treatment, and the lowest dose is 125mg per day. The clinical symptoms, signs and adverse reactions of patients were observed, and the treatment effect of patients was evaluated after two consecutive cycles with 3 weeks as a cycle.
cisplatin
on the first day of treatment, patients were given 80mg/m2 cisplatin intravenously, and 21 days was a course of treatment, lasting for 6 courses.
Hangzhou first people's Hospital, Hangzhou
College of Pharmaceutical Sciences at Zhejiang University
UNKNOWN
The Innovation Institute for Artificial Intelligence in Medicine, Zhejiang University
UNKNOWN
First People's Hospital of Hangzhou
OTHER