Effects of Exercise on Dystonia Pathophysiology

NARecruitingINTERVENTIONAL
Enrollment

56

Participants

Timeline

Start Date

October 13, 2022

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2027

Conditions
Dystonia
Interventions
BEHAVIORAL

Progressive resistance exercise

Patients with predominant symptoms of cervical dystonia will receive exercise training. Patients will receive progressive resistance exercise focused cervical and shoulder training (PERFECT) plus standard-of-care (SOC) therapy. Resistance training will consist of mainly muscle-strengthening exercises for the neck, shoulder and arms and a few upper trunk muscles. Resistance training will be guided by physical therapists at twice a week schedule for 6 months. These participants will also receive SOC therapy.

BEHAVIORAL

Standard of care

Subjects will receive SOC therapy only

Trial Locations (1)

32611

RECRUITING

University of Florida, Gainesville

All Listed Sponsors
collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

lead

University of Florida

OTHER