A Study to Investigate the Antitumor Activity, Safety, Tolerability, and Pharmacokinetics of BGB-A445 in Combination With Tislelizumab in Participants With Select Advanced Solid Tumors.

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

202

Participants

Timeline

Start Date

January 19, 2023

Primary Completion Date

October 31, 2026

Study Completion Date

October 31, 2026

Conditions
Urothelial CarcinomaRenal Cell CarcinomaMelanomaNon-mucosal Melanoma
Interventions
DRUG

BGB-A445

administered intravenously

DRUG

Tislelizumab

administered intravenously

Trial Locations (18)

100142

Beijing Cancer Hospital, Beijing

110042

Liaoning Cancer Hospital and Institute, Shenyang

130021

The First Hospital of Jilin University, Changchun

210008

Nanjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School, Nanjing

250117

Shandong Cancer Hospital, Jinan

272000

Jining No Peoples Hospital West Branch, Jining

300060

Tianjin Medical University Cancer Institute and Hospital, Tianjin

325000

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou

350014

Fujian Cancer Hospital, Fuzhou

410011

The Second Xiangya Hospital of Central South University, Changsha

430030

Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology, Wuhan

450052

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

510000

Zhujiang Hospital of Southern Medical University, Guangzhou

510060

Sun Yat Sen University Cancer Center, Guangzhou

530021

The Tumor Hospital Affiliated to Guangxi Medical University, Nanning

610041

West China Hospital, Sichuan University, Chengdu

730030

The Second Hospital and Clinical Medical School, Lanzhou University, Lanzhou

030013

Shanxi Provincial Cancer Hospital, Taiyuan

Sponsors

Lead Sponsor

All Listed Sponsors
lead

BeiGene

INDUSTRY