Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

NARecruitingINTERVENTIONAL
Enrollment

768

Participants

Timeline

Start Date

March 6, 2024

Primary Completion Date

March 1, 2027

Study Completion Date

March 1, 2028

Conditions
Smoking CessationSmoking, CigaretteSmoking ReductionSmokingSmoking, TobaccoQuitting Smoking
Interventions
DRUG

4 weeks of Nicotine lozenge

All participants will receive at least 4 weeks of the NRT Patch. Some will be randomized to receive 4 weeks of lozenge in addition to the NRT Patch. NRT temporarily replaces nicotine from tobacco to reduce motivation to consume tobacco and nicotine withdrawal symptoms.

DRUG

8 weeks of Nicotine Replacement Therapy Patch

All participants will receive at least 4 weeks of the NRT Patch. Some will also be randomized to receive an additional 4 weeks of the NRT Patch

BEHAVIORAL

QuitAid

All participants will receive at least 4 weeks of the NRT Patch. Some participants will also be randomized to receive the QuitAid intervention, based on a medication adherence intervention, addresses perceptions (e.g., motivation, self-efficacy, beliefs) and practicalities of using NRT (e.g., monitoring NRT use, establishing a reminder system). QuitAid includes 1 in-person session and 5 follow-up telephonic sessions with the participant's local pharmacist/technician.

BEHAVIORAL

Smokefree TXT

All participants will receive at least 4 weeks of the NRT Patch. Some participants will also be randomized to receive the SmokefreeTXT is a text-messaging program offered through the National Cancer Institute's Smokefree.gov initiative, which sends pre-programmed messages timed around a quit date. Participants will receive 3-5 messages a day for 7 weeks. The first week of messages focus on preparation and the remaining 6 weeks of messages focus on post-cessation strategies (e.g., relapse prevention), all timed relative to the quit date set at enrollment.

BEHAVIORAL

Tobacco Quitline

All participants will receive at least 4 weeks of the NRT Patch. Some participants will also be randomized to receive a 4-session proactive tobacco quitline, with each session lasting 20-30 minutes and occurring on days 7, 14, 21 and 28.The quitline intervention incorporates 3 phases: (1) preparing to quit, (2) quitting process, and (3) relapse prevention.

DRUG

4 weeks of Nicotine Replacement Therapy Patch

All participants will receive at least 4 weeks of the NRT Patch.

DRUG

8 Weeks Nicotine Lozenge

All participants will receive at least 4 weeks of the NRT Patch. Some will be randomized to receive 8 weeks of lozenge in addition to the NRT Patch. NRT temporarily replaces nicotine from tobacco to reduce motivation to consume tobacco and nicotine withdrawal symptoms.

Trial Locations (1)

22904

RECRUITING

University of Virginia, Charlottesville

All Listed Sponsors
lead

University of Virginia

OTHER