60
Participants
Start Date
January 3, 2023
Primary Completion Date
March 31, 2027
Study Completion Date
July 30, 2027
Acetylcholine
acetylcholine, and acetylcholine + L-NAME (Nitric oxide synthase inhibitor) are locally and acutely delivered to the cutaneous microvasculature to assess endothelium- and nitric oxide-dependent dilation
Endothelin-1
endothelin-1, endothelin-1 + BQ-788 (endothelin receptor type B-inhibitor), and endothelin-1 + BQ-123 (endothelin receptor type A-inhibitor) are locally and acutely delivered to the cutaneous microvasculature to assess endothelin-mediated constriction and the role of the receptor subtypes in this response.
RECRUITING
University of Iowa, Iowa City
Anna Stanhewicz, PhD
OTHER