GPC2 CAR T Cells for Relapsed or Refractory Neuroblastoma and Metastatic Retinoblastoma

PHASE1RecruitingINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

May 23, 2023

Primary Completion Date

January 30, 2028

Study Completion Date

January 30, 2030

Conditions
Refractory NeuroblastomaRelapsed NeuroblastomaHigh-risk NeuroblastomaRetinoblastomaMetastatic Retinoblastoma
Interventions
BIOLOGICAL

GPC2 CAR T cells

The GPC2 CAR T investigational product is comprised of autologous human T cells that have been genetically modified to express a GPC2-targeting chimeric antigen receptor (CAR) transgene.

Trial Locations (1)

19104

RECRUITING

Children's Hospital of Philadelphia, Philadelphia

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Children's Hospital of Philadelphia

OTHER

collaborator

Gilead Sciences

INDUSTRY

collaborator

University of Pennsylvania

OTHER

collaborator

National Cancer Institute (NCI)

NIH

collaborator

Kite, A Gilead Company

INDUSTRY

lead

Stephan Grupp MD PhD

OTHER

NCT05650749 - GPC2 CAR T Cells for Relapsed or Refractory Neuroblastoma and Metastatic Retinoblastoma | Biotech Hunter | Biotech Hunter