Efficacy and Safety of Dupilumab in Patients With Bullous Pemphigoid

CompletedOBSERVATIONAL
Enrollment

146

Participants

Timeline

Start Date

September 1, 2022

Primary Completion Date

December 31, 2022

Study Completion Date

January 31, 2023

Conditions
Bullous Pemphigoid
Interventions
DRUG

Dupilumab

Duplimab was administered according to the guidelines of the atopic dermatitis treatment regimen, which involved the first dose of 600 mg followed by 300 mg every two weeks. Because of comorbidities or the side effects of corticosteroid, some patients used dupilumab in the initial course of treatment, while others added dupilumab when the traditional drugs proved ineffective. The discontinuation was a joint decision between treating dermatologists and patients. Concomitant medicine was decided by clinicians, depending on the assessing of disease status and patients' choices, and reduced according to international guidelines.

Trial Locations (1)

100034

Peking University First Hospital, Beijing

All Listed Sponsors
collaborator

Ruijin Hospital

OTHER

collaborator

Chinese Academy of Medical Sciences

OTHER

collaborator

West China Hospital

OTHER

collaborator

Second Xiangya Hospital of Central South University

OTHER

collaborator

Shandong Provincial Institute of Dermatology and Venereology

OTHER

lead

Peking University First Hospital

OTHER