Comparing of Cefazolin Plus Azithromycin Versus Cefazolin in Prevention of Febrile Morbidity After Emergency Cesarean Delivery

NACompletedINTERVENTIONAL
Enrollment

172

Participants

Timeline

Start Date

December 14, 2022

Primary Completion Date

November 30, 2023

Study Completion Date

December 30, 2023

Conditions
Febrile Morbidity After Emergency Cesarean Section
Interventions
DRUG

Azithromycin Injection [Zithromax]

Intervention group patient will receive standard antimicrobial prophylaxis(cefazolin intravenously weight dependent) and azithromycin 500 mg intravenously before the incision

DRUG

Cefazolin

All the participants will receive the cefazolin intravenously. The dosage of the cefazolin is depend on participant's weight. The participant with weight less than 80kg will receive cefazolin 1 gm and between 80-120kg will receive cefazolin 2 gm and for the participant with more than 120kg will receive cefazolin 3 gm before the incision.

DRUG

Sodium Chloride 0.9% Intravenous Solution

For the placebo group will receive the cefazolin intravenously and 0.9% NaCl 100ml before the incision

Trial Locations (1)

10400

Rajavithi Hospital, Bangkok

All Listed Sponsors
lead

Department of Medical Services Ministry of Public Health of Thailand

OTHER_GOV