NCT05646992View on ClinicalTrials.gov

Uterus Transplantation to Treat Infertility

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

March 1, 2023

Primary Completion Date

February 28, 2033

Study Completion Date

February 28, 2043

Conditions
Uterine Factor Infertility
Interventions
PROCEDURE

Uterine Allotransplantation

Temporary allogenic uterus transplantation from a living donor with the goal of achieving pregnancy and delivering viable baby.

DRUG

Tacrolimus

Used as daily immunosuppression. Started at 3mg twice daily (PO) on post-operative Day 1, adjusted to achieve serum trough concentrations of 8-10ng/ml.

DRUG

Imuran

Used as daily immunosuppresion. 100 mg for total body weight less than 75 kg and 150 mg for total body weight greater than or equal to 75 mgs

Trial Locations (1)

21287

RECRUITING

Johns Hopkins University School of Medicine, Baltimore

All Listed Sponsors
lead

Johns Hopkins University

OTHER