Evaluation of 611 in Chinese Adult Patients With Moderate-to-Severe Atopic Dermatitis

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

October 18, 2021

Primary Completion Date

October 21, 2022

Study Completion Date

October 21, 2022

Conditions
Dermatitis, Atopic
Interventions
DRUG

611 150mg

subcutaneous injection, 150 mg (single dose treatment period) + 300mg (loading dose, week 0) + 150mg QW (maintenance dose, from Week 1 to Week 15, 15 cycles)

DRUG

611 300mg

subcutaneous injection, 300 mg (single dose treatment period) + 600mg (loading dose, week 0) + 300mg Q2W (maintenance dose, from Week 1 to Week 15, 8 cycles)

DRUG

611 600mg

subcutaneous injection, 600 mg (single dose treatment period) + 600mg (loading dose, week 0) + 300mg QW (maintenance dose, from Week 1 to Week 15, 15 cycles)

OTHER

Placebo

During the study, placebos shall be filled timely according to the administration of the test drug to ensure the consistency of the times of administration in each group, so as to maintain the blind state.

Trial Locations (5)

100144

Peking University Shougang Hospital, Beijing

110001

The First of Hospital China Medical University, Shenyang

241001

The First Affiliated Hospital of Wannan Medical College, Wuhu

330001

Dermatology Hospital of Jiangxi Province, Nanchang

473010

Nanyang First People's Hospital, Nanyang

All Listed Sponsors
lead

Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.

INDUSTRY

NCT05641558 - Evaluation of 611 in Chinese Adult Patients With Moderate-to-Severe Atopic Dermatitis | Biotech Hunter | Biotech Hunter