The Origin and Role of Thromboembolism in the Pathogenesis of Ischaemic Stroke

Patient will receive 1 18F-GP1 PET/CT

Agitated saline and ultrasound contrast will be performed to assess for intracardiac shunts and left ventricular thrombus.

Where necessary, if the CT head is normal or the clinical diagnosis of a stroke is not definite, a research MRI head will be undertaken if this has not already been performed as part of standard care.

All patients who do not have evidence of atrial fibrillation or atrial flutter on their 12-lead ECG will undergo an ECG Holter monitor for up to 7 days. This will be part of their standard care. If this has not been arranged by the usual care team this will be performed as a research procedure.