38
Participants
Start Date
June 30, 2023
Primary Completion Date
December 15, 2024
Study Completion Date
December 15, 2025
Autologous CD19-STAR-T cell
Phase 1 dose escalation (3+3) : dose 1 (1×10\^6 cells/kg) ,dose 2 (3×10\^6 cells/kg) ,dose 3 (1×10\^7 cells/kg); Phase 2 : Appropriate dose
Fludarabine
Intravenous fludarabine 25-30 mg/m\^2/day on days -5, -4, and -3.
Cyclophosphamide
Intravenous cyclophosphamide 300-500 mg/m\^2/day on days -5, -4, and -3.
RECRUITING
Biotherapeutic Department, Chinese PLA General Hospital, Beijing
RECRUITING
School of medicine, Tsinghua University & Changping Laboratory, Beijing
Chinese PLA General Hospital
OTHER