Primary carE PPi dEprescRibing Trial

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

724

Participants

Timeline

Start Date

May 12, 2023

Primary Completion Date

March 1, 2026

Study Completion Date

June 1, 2026

Conditions
HeartburnDyspepsiaReflux
Interventions
PROCEDURE

de-prescription of PPI via intermittent scheme

The patients will decrease their intake of PPIs via a de-prescription intermittent scheme. After one month, patients will stop their intake of PPI.

PROCEDURE

de-prescription of PPI via on-demand scheme

The patients will decrease their intake of PPIs via a de-prescription on-demand scheme. After one month, patients will stop their intake of PPI.

DRUG

Alginate

The patients will stop their intake of PPIs and use alginate. After one month, patients will stop their intake of alginates.

Trial Locations (1)

3000

Jan Tack, Leuven

All Listed Sponsors
lead

Universitaire Ziekenhuizen KU Leuven

OTHER