TrEatment Approach in the Multimodal Era Registry

Active, not recruitingOBSERVATIONAL
Enrollment

1,000

Participants

Timeline

Start Date

April 12, 2023

Primary Completion Date

April 30, 2028

Study Completion Date

April 30, 2028

Conditions
Chronic Thromboembolic Pulmonary HypertensionCTEPH
Interventions
PROCEDURE

Pulmonary endarterectomy

Surgical removal of a chronic clot from the pulmonary artery

PROCEDURE

Balloon pulmonary angioplasty

Catheter-based intervention to dilate occluded pulmonary vessels through the insertion and inflation of a small balloon

DRUG

Pulmonary hypertension (PH)-specific medication

Treatment with any PH-specific medication, i.e. endothelin receptor antagonists, phosphodiesterase type 5 inhibitors, soluble guanylate cyclase stimulators, drugs acting on the prostanoid pathway and prostaglandin I2 receptor agonists

Trial Locations (25)

1090

University Hospital Vienna, Vienna

3000

University Hospitals Leuven, Leuven

8200

Aarhus University Hospital, Aarhus

12808

General University Hospital, Prague

14080

National Heart Institute, Mexico City

27705

Duke University, Durham

28041

Pulmonary Hypertension Unit, Hospital 12 de Octubre, Madrid

34899

Marmara University School of Medicine, Istanbul

40126

University of Bologna, Bologna

60208

Northwestern University, Evanston

61231

Kerckhoff Clinic, Department of Thoracic Surgery, Bad Nauheim

75390

UT Southwestern, Dallas

92037

University of California San Diego, San Diego

100020

China-Japan Friendship Hospital, Beijing

111121

Shaio Clinic Foundation, Bogotá

168582

National Heart Centre of Singapore, Singapore

560099

Narayana Institute of Cardiac Science, Bangalore

C1093AAS

Hospital Universitario Fundación Favaloro, Buenos Aires

RS 90035-074

Santa Casa, Porto Alegre

M5G 2C4

Toronto General Hospital, Toronto

701-1192

Okayama Medical Center, Okayama

564-8565

National Cerebral and Cardiovascular Center, Osaka

31-202

Department of Cardiac and Vascular Diseases, John Paul II Hospital, Krakow

05-400

Department of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, European Health Center Otwock, Otwock

CB2 0AY

Royal Papworth Hospital, Cambridge

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Janssen Pharmaceuticals

INDUSTRY

lead

International CTEPH Association

OTHER

NCT05629052 - TrEatment Approach in the Multimodal Era Registry | Biotech Hunter | Biotech Hunter