The Combination of Hypofractionated Radiotherapy and Immunotherapy in Locally Recurrent Rectal Cancer

PD-1 antibody (Toripalimab): 240mg q3w or 160mg q2w

Capecitabine: 1000mg/m2 d1-14 q3w

400 mg/m2 (bolus) and 2400 mg/m2 (continuous infusion for 48hr)

400 mg/m2 q2w

130 mg/m² q3w or 85 mg/m² q2w

180 mg/m² q2w and 200 mg/m² q3w

2 mg/m² q2w and 3 mg/m² q3w

400 mg/m² q2w

5 mg/kg q2w or 7.5mg/kg q3w

"25-40Gy/5Fx irradiation or 15-30Gy/5Fx reirradiation (pelvic radiation history) for pelvic recurrence tumor.~35-60Gy/5-8Fx irradiation for distance metastasis tumor."