NCT05622708 - A Study of Secukinumab to Evaluate Maintenance of Response in Participants With Non-radiographic Axial Spondyloarthritis Who Achieved Remission | Biotech Hunter

Enrollment

340

Participants

Timeline

Start Date

March 28, 2023

Primary Completion Date

April 26, 2030

Study Completion Date

June 21, 2030

Conditions

Non-radiographic Axial Spondyloarthritis

Interventions

DRUG

Secukinumab

Treatment Period 1: Open-label secukinumab 150 mg PFS s.c. at baseline, Weeks 1, 2, 3 and 4 followed by administration every four weeks up to Week 52.

DRUG

Placebo

Treatment Period 2: Double-blind placebo PFS s.c. every 4 weeks from Week 56 to Week 116.

DRUG

Secukinumab

"Treatment Period 2: Double-blind secukinumab 150 mg PFS s.c. every 4 weeks from Week 56 to Week 116.~Escape re-treatment (during Treatment Period 2): Open-label secukinumab 150 mg PFS s.c."

Trial Locations (88)

1008

RECRUITING

Novartis Investigative Site, Manila

1023

RECRUITING

Novartis Investigative Site, Budapest

1218

RECRUITING

Novartis Investigative Site, Makati City

1230

RECRUITING

Novartis Investigative Site, Adana

2143

RECRUITING

Novartis Investigative Site, Kistarcsa

3300

RECRUITING

Novartis Investigative Site, Eger

3526

RECRUITING

Novartis Investigative Site, Miskolc

3600

RECRUITING

Novartis Investigative Site, Genk

3712

RECRUITING

Novartis Investigative Site, Verona

4032

RECRUITING

Novartis Investigative Site, Debrecen

6720

RECRUITING

Novartis Investigative Site, Szeged

7000

RECRUITING

Novartis Investigative Site, Mons

8000

RECRUITING

Novartis Investigative Site, Bruges

RECRUITING

Novartis Investigative Site, Székesfehérvár

8200

RECRUITING

Novartis Investigative Site, Veszprém

9000

RECRUITING

Novartis Investigative Site, Ghent

10128

RECRUITING

Novartis Investigative Site, Torino

10400

RECRUITING

Novartis Investigative Site, Bangkok

10700

RECRUITING

Novartis Investigative Site, Bangkok

12161

RECRUITING

Novartis Investigative Site, Berlin

13125

RECRUITING

Novartis Investigative Site, Berlin

13353

WITHDRAWN

Novartis Investigative Site, Berlin

18209

RECRUITING

Novartis Investigative Site, Bad Doberan

20100

RECRUITING

Novartis Investigative Site, Milan

22415

RECRUITING

Novartis Investigative Site, Hamburg

24768

RECRUITING

Novartis Investigative Site, Rendsburg

30599

WITHDRAWN

Novartis Investigative Site, Plzen Bory

31000

RECRUITING

Novartis Investigative Site, Chihuahua City

31059

RECRUITING

Novartis Investigative Site, Toulouse

34899

ACTIVE_NOT_RECRUITING

Novartis Investigative Site, Istanbul

37024

RECRUITING

Novartis Investigative Site, Negrar

37170

RECRUITING

Novartis Investigative Site, Chambray-lès-Tours

39110

RECRUITING

Novartis Investigative Site, Magdeburg

40136

RECRUITING

Novartis Investigative Site, Bologna

40878

RECRUITING

Novartis Investigative Site, Ratingen

42080

RECRUITING

Novartis Investigative Site, Konya

44649

RECRUITING

Novartis Investigative Site, Herne

44650

RECRUITING

Novartis Investigative Site, Guadalajara

44690

RECRUITING

Novartis Investigative Site, Guadalajara

45100

RECRUITING

Novartis Investigative Site, Orléans

50134

RECRUITING

Novartis Investigative Site, Florence

53100

RECRUITING

Novartis Investigative Site, Siena

59100

RECRUITING

Novartis Investigative Site, Kuala Lumpur

60126

RECRUITING

Novartis Investigative Site, Ancona

67063

RECRUITING

Novartis Investigative Site, Ludwigshafen

68100

RECRUITING

Novartis Investigative Site, Selangor Darul Ehsan

72000

RECRUITING

Novartis Investigative Site, Le Mans

75012

RECRUITING

Novartis Investigative Site, Paris

79106

RECRUITING

Novartis Investigative Site, Freiburg im Breisgau

93586

RECRUITING

Novartis Investigative Site, Kuching

97070

RECRUITING

Novartis Investigative Site, Mérida

110111

RECRUITING

Novartis Investigative Site, Bogota

110221

RECRUITING

Novartis Investigative Site, Bogotá

250001

RECRUITING

Novartis Investigative Site, Chía

400006

RECRUITING

Novartis Investigative Site, Cluj-Napoca

500283

RECRUITING

Novartis Investigative Site, Brasov

550245

RECRUITING

Novartis Investigative Site, Sibiu

680003

RECRUITING

Novartis Investigative Site, Bucaramanga

700000

RECRUITING

Novartis Investigative Site, Ho Chi Minh City

RECRUITING

Novartis Investigative Site, Ho Chi Minh City

727525

RECRUITING

Novartis Investigative Site, Suceava

3104802

RECRUITING

Novartis Investigative Site, Haifa

4428164

RECRUITING

Novartis Investigative Site, Kfar Saba

5265601

RECRUITING

Novartis Investigative Site, Ramat Gan

6423906

RECRUITING

Novartis Investigative Site, Tel Aviv

36010 570

RECRUITING

Novartis Investigative Site, Juiz de Fora

90480-000

RECRUITING

Novartis Investigative Site, Porto Alegre

14784 400

RECRUITING

Novartis Investigative Site, Barretos

01409-902

WITHDRAWN

Novartis Investigative Site, São Paulo

080020

RECRUITING

Novartis Investigative Site, Barranquilla

128 00

RECRUITING

Novartis Investigative Site, Prague

148 00

RECRUITING

Novartis Investigative Site, Prague

150 06

RECRUITING

Novartis Investigative Site, Prague

686 01

RECRUITING

Novartis Investigative Site, Uherské Hradiště

06001

RECRUITING

Novartis Investigative Site, Nice

00161

RECRUITING

Novartis Investigative Site, Roma

6419 PC

RECRUITING

Novartis Investigative Site, Heerlen

6229 HX

RECRUITING

Novartis Investigative Site, Maastricht

1105 AZ

RECRUITING

Novartis Investigative Site, Amsterdam

30-727

RECRUITING

Novartis Investigative Site, Krakow

15-351

RECRUITING

Novartis Investigative Site, Bialystok

85 168

RECRUITING

Novartis Investigative Site, Bydgoszcz

30-002

RECRUITING

Novartis Investigative Site, Krakow

96-500

RECRUITING

Novartis Investigative Site, Sochaczew

87-100

RECRUITING

Novartis Investigative Site, Torun

02 637

RECRUITING

Novartis Investigative Site, Warsaw

011055

RECRUITING

Novartis Investigative Site, Bucharest

011172

RECRUITING

Novartis Investigative Site, Bucharest