NCT05621291View on ClinicalTrials.gov

A Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymphoblastic Leu...

NARecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

October 28, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2027

Conditions
B-AllAcute Lymphoblastic Leukemia
Interventions
DIAGNOSTIC_TEST

NGS testing

antigen immunophenotype agnostic approach for disease detection using blood and bone marrow samples

Trial Locations (8)

20010

RECRUITING

Children's National Medical Center, Washington D.C.

20892

RECRUITING

National Institutes of Health Clinical Center, Bethesda

30329

NOT_YET_RECRUITING

Children's Healthcare of Atlanta, Atlanta

84112

RECRUITING

Huntsman Cancer Institute, University of Utah, Salt Lake City

90027

RECRUITING

Children's Hospital of Los Angeles, Los Angeles

98105

RECRUITING

Seattle Children's, University of Washington, Seattle

98109

RECRUITING

Fred Hutchinson Cancer Research Center, Seattle

02115

NOT_YET_RECRUITING

Dana-Farber/Boston Children s Hospital, Boston

All Listed Sponsors
lead

National Cancer Institute (NCI)

NIH