9
Participants
Start Date
August 9, 2023
Primary Completion Date
July 15, 2025
Study Completion Date
June 1, 2026
Darolutamide
Tablet administered orally, per protocol, 2 x daily. Darolutamide is an orally administered molecular drug therapy that blocks the action of testosterone, the male sex hormone which can stimulate growth of prostate cancer.
Abemaciclib
"Tablet administered orally, per protocol, 2 x daily. Abemaciclib is an orally administered molecular drug therapy that is called a CDK4/6 inhibitor. CDK4 and CDK6 are enzymes that are involved in helping healthy and cancerous cells divide and blocking these enzymes can stop cancerous cells from growing."
GNRH-A Leuprolide Acetate
Administered via intramuscular injection, per standard of care. GnRH agonist is a hormonal therapy drug.
GNRH-A Goserelin
Administered via subcutaneous injection, per standard of care. GnRH agonist is a hormonal therapy drug.
Degarelix
Administered via subcutaneous injection, per standard of care. GnRH antagonist is a hormonal therapy drug.
Dana-Farber Cancer Institute, Boston
Collaborators (1)
Eli Lilly and Company
INDUSTRY
Bayer
INDUSTRY
Praful Ravi, MB BCHir, MRCP
OTHER