Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate Tumor

PHASE2RecruitingINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

October 19, 2023

Primary Completion Date

December 1, 2027

Study Completion Date

December 1, 2028

Conditions
Prostatic NeoplasmsProstate CancerProstate Adenocarcinoma
Interventions
DRUG

18F-DCFPyL

Each participant will receive a single IV dose of 18F-DCFPyL by bolus injection. The target administered activity will be 6.5 mCi with a lower limit of 6 mCi; dose variations will be in accordance with the Nuclear Regulatory Commission (NRC) standard dose variation (i.e., 20%) permitted for diagnostic clinical studies.

RADIATION

Stereotactic Body Radiation Therapy

Intensity modulated radiotherapy will be delivered to a dose of 26Gy in two fractions with the second fraction performed within 8 days of the first session.

Trial Locations (1)

20892

RECRUITING

National Institutes of Health Clinical Center, Bethesda

All Listed Sponsors
lead

National Cancer Institute (NCI)

NIH