20
Participants
Start Date
February 21, 2023
Primary Completion Date
February 19, 2025
Study Completion Date
February 19, 2025
Clinical assessment
MS history and MS treatments and Expanded Disability Status Scale (EDSS) score will be recorded
Classical cognitive evaluation of several domains:
Information processing speed (IPS) Working memory (WM) Executive functions (EF) Episodic memory (EM) Premorbid intelligence quotient (IQ) Multidomain or complex task
Ecological evaluation
Virtual reality task : Urban DailyCog©
Patent reported outcomes (PRO's)
"Patent reported outcomes (PRO's) : Beck Depression Inventory (BDI), European Quality of Life-5 Dimensions (EQ-5D-5L) for Health-Related Quality of Life (HRQOL), Multiple Sclerosis Impact Scale-29 Items (MSIS-29), French version of the Modified Fatigue Impact Scale (EMISEP) and State trait anxiety inventory (STAI).~Subjective cognitive deficits: Perceived Deficits Questionnaire (PDQ) and Cognitive Activities Questionnaire (DCAQ)"
Telerehabilitation : active procedure
The Cognitive rehabilitation (CR) consists of weekly 45 minutes online individual session with the unblinded Speech Therapist.
Telerehabilitation : comparator procedure
Once per week over a 12-week period completed by daily online exercises performed by the patient 4 days a week.
CHU de Bordeaux - Service de neurologie, Bordeaux
CHU de Clermont-Ferrand - Service de neurologie, Clermont-Ferrand
CHU de Dijon-Bourgogne - Service de neurologie, Dijon
CH de Dunkerque - Service de neurologie, Dunkirk
Hôpital Saint Vincent de Paul - Service de neurologie, Lille
CHU de Montpellier - Service de neurologie, Montpellier
CHI Hôpital de Poissy Saint Germain en Laye - Service de neurologie, Poissy
Collaborators (1)
Celgene
INDUSTRY
University Hospital, Bordeaux
OTHER