Telerehabilitation of Multidomain Cognitive Impairment in Multiple Sclerosis

NATerminatedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

February 21, 2023

Primary Completion Date

February 19, 2025

Study Completion Date

February 19, 2025

Conditions
Multiple Sclerosis
Interventions
OTHER

Clinical assessment

MS history and MS treatments and Expanded Disability Status Scale (EDSS) score will be recorded

OTHER

Classical cognitive evaluation of several domains:

Information processing speed (IPS) Working memory (WM) Executive functions (EF) Episodic memory (EM) Premorbid intelligence quotient (IQ) Multidomain or complex task

OTHER

Ecological evaluation

Virtual reality task : Urban DailyCog©

BEHAVIORAL

Patent reported outcomes (PRO's)

"Patent reported outcomes (PRO's) : Beck Depression Inventory (BDI), European Quality of Life-5 Dimensions (EQ-5D-5L) for Health-Related Quality of Life (HRQOL), Multiple Sclerosis Impact Scale-29 Items (MSIS-29), French version of the Modified Fatigue Impact Scale (EMISEP) and State trait anxiety inventory (STAI).~Subjective cognitive deficits: Perceived Deficits Questionnaire (PDQ) and Cognitive Activities Questionnaire (DCAQ)"

OTHER

Telerehabilitation : active procedure

The Cognitive rehabilitation (CR) consists of weekly 45 minutes online individual session with the unblinded Speech Therapist.

OTHER

Telerehabilitation : comparator procedure

Once per week over a 12-week period completed by daily online exercises performed by the patient 4 days a week.

Trial Locations (7)

Unknown

CHU de Bordeaux - Service de neurologie, Bordeaux

CHU de Clermont-Ferrand - Service de neurologie, Clermont-Ferrand

CHU de Dijon-Bourgogne - Service de neurologie, Dijon

CH de Dunkerque - Service de neurologie, Dunkirk

Hôpital Saint Vincent de Paul - Service de neurologie, Lille

CHU de Montpellier - Service de neurologie, Montpellier

CHI Hôpital de Poissy Saint Germain en Laye - Service de neurologie, Poissy

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Celgene

INDUSTRY

lead

University Hospital, Bordeaux

OTHER