Efficacy of Preconditioned Adipose-Derived Stem Cells in Fat Grafting

PHASE1RecruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

November 20, 2020

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Romberg DiseaseCraniofacial MicrosomiaBurn ScarPost-Traumatic Scar (Disorder)
Interventions
BIOLOGICAL

Cultured ASCs enrichment fat grafting

Patients will undergo conventional fat harvesting. Harvested fat will be mixed with cultured ASCs and grafted into recipient site with 1,00,000 cells/ml injected fat

BIOLOGICAL

Curcumin-preconditioned ASCs enrichment fat grafting

Patients will undergo conventional fat harvesting. Harvested fat will be mixed with cultured ASCs preconditioned with curcumin and grafted into recipient site with 1,00,000 cells/ml injected fat

OTHER

Conventional fat grafting

Patients will undergo conventional fat harvesting and grafting of fat into recipient site

Trial Locations (1)

54550

RECRUITING

Stem Cell Laboratory, Jinnah Burn and Reconstructive Surgery Center (JB&RSC), Lahore

All Listed Sponsors
collaborator

Centre of Excellence in Molecular Biology, University of the Punjab, Lahore

UNKNOWN

collaborator

Higher Education Commission (Pakistan)

OTHER

collaborator

Jinnah Burn and Reconstructive Surgery Centre, Lahore

OTHER_GOV

lead

University of the Punjab

OTHER