Hormonal Influences on Inflammatory Bowel Diseases

NANot yet recruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

December 1, 2024

Primary Completion Date

August 1, 2026

Study Completion Date

March 1, 2027

Conditions
Inflammatory Bowel DiseasesContraceptionMenstrual Problem
Interventions
OTHER

Proposed study design and randomization scenarios

Present hypothetical study scenarios and assess willingness to be randomized based on the adapted 7-item Attitudes to Randomized Trials Questionnaire

OTHER

Repeated measures of validated Inflammatory Bowel Disease Patient Reported Outcome Instruments

We will electronically administer Ulcerative Colitis (UC) and Crohn's Disease validated PRO instruments, including the daily symptom modules and weekly quality of life modules for 12 weeks to all 200 participants

OTHER

Inflammatory marker collection and assessment for correlation with PRO responses and menstrual timing

In an Aim 3 sub study of 30% of participants, we will collect inflammatory markers commonly used to assess disease activity and risk of relapse in inflammatory bowel disease patients, including weekly blood samples of high sensitivity c-reactive protein (13 total) and monthly ferritin, albumin, and WBC, as well monthly stool specimens (4 total) for fecal calprotectin

Trial Locations (1)

84132

University of Utah, Salt Lake City

All Listed Sponsors
lead

University of Utah

OTHER

NCT05610527 - Hormonal Influences on Inflammatory Bowel Diseases | Biotech Hunter | Biotech Hunter