Study the Effect of Omeprazole on AB-106 Pharmacokinetics

PHASE1CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

November 2, 2022

Primary Completion Date

January 20, 2023

Study Completion Date

January 20, 2023

Conditions
Pharmacokinetic Study
Interventions
DRUG

Multiple administration of omeprazole Single administration of AB-106

Take AB-106 capsule 400 mg orally on an empty stomach in the morning of the first day of the first cycle Take omeprazole magnesium enteric coated tablets 40mg once a day, 30 minutes before breakfast on days 1-4 of the second cycle. On the morning of the fifth day of the second cycle, the subjects will take omeprazole magnesium enteric coated tablets 40 mg, and AB-106 capsules 400 mg after an interval of 1 hour

Trial Locations (1)

Unknown

Shanghai Xuhui Central Hospital, Shanghai

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

AnHeart Therapeutics Inc.

INDUSTRY

lead

Nuvation Bio Inc.

INDUSTRY