U87 CART in Treatment of Advanced Solid Tumor

PHASE1RecruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

October 19, 2022

Primary Completion Date

December 31, 2024

Study Completion Date

October 8, 2025

Conditions
Pancreatic CancerSolid Tumor, Adult
Interventions
DRUG

U87 CAR-T

Subjects will be pretreated with cyclophosphamide 250\~500 mg/m2( body surface area) for 3 days prior to Intravenous injection of U87, followed by intraartery of U87 14 days later with intravenous IL-2. Researchers can perform intratumoral injection based on their judgment.This study will explore two dose of dose 1 (DL-1): 1×106 (±20%) to dose 2 (DL-2): 1×107 (±20%),each group was enrolled in 3\~6 patients.

Trial Locations (1)

Unknown

RECRUITING

China Shanghai 10th People's Hospital, Shanghai

All Listed Sponsors
collaborator

Shanghai 10th People's Hospital

OTHER

lead

Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd

INDUSTRY