12
Participants
Start Date
October 19, 2022
Primary Completion Date
December 31, 2024
Study Completion Date
October 8, 2025
U87 CAR-T
Subjects will be pretreated with cyclophosphamide 250\~500 mg/m2( body surface area) for 3 days prior to Intravenous injection of U87, followed by intraartery of U87 14 days later with intravenous IL-2. Researchers can perform intratumoral injection based on their judgment.This study will explore two dose of dose 1 (DL-1): 1×106 (±20%) to dose 2 (DL-2): 1×107 (±20%),each group was enrolled in 3\~6 patients.
RECRUITING
China Shanghai 10th People's Hospital, Shanghai
Shanghai 10th People's Hospital
OTHER
Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd
INDUSTRY