A Study Utilizing Patient-Reported Outcomes to Evaluate the Safety and Efficacy of Lorecivivint (SM04690) for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthritis (STRIDES)

PHASE3CompletedINTERVENTIONAL
Enrollment

496

Participants

Timeline

Start Date

November 18, 2022

Primary Completion Date

February 20, 2024

Study Completion Date

February 20, 2024

Conditions
Knee Osteoarthritis
Interventions
DRUG

Lorecivivint

One intra-articular injection of 0.07 mg lorecivivint in 2 mL vehicle

DRUG

Placebo

One intra-articular injection of 0 mg lorecivivint in 2 mL vehicle

Trial Locations (44)

20852

DelRicht Research - Rockville, Rockville

29406

Clinical Trials of South Carolina, Charleston

29707

Piedmont Research Partners, LLC, Fort Mill

30281

Pinnacle Trials, Inc., Stockbridge

32159

Premier Medical Associates, The Villages

32789

Conquest Research, LLC, Winter Park

33013

Eastern Research, Inc., Hialeah

33024

TecTum Research, Hollywood

33125

Columbus Clinical Services, LLC, Miami

33126

AppleMed Research Group, LLC, Miami

33135

Advance Medical Research Center, Miami

33155

Health and Life Research Institute, LLC, Miami

33156

BioMed Research and Medical Center, Miami

33166

South Florida Research Phase I-IV, Inc., Miami Springs

33172

Unique Clinical Trials, Doral

33173

Well Pharma Medical Research, Corp, Miami

33603

Tampa Pain Relief Center, Tampa

45224

Hightop Medical Research Center, Cincinnati

47714

MediSphere Medical Research Center, LLC, Evansville

48085

Oakland Medical Research, Troy

57702

Health Concepts, Rapid City

60607

Chicago Clinical Research Institute, Chicago

63042

Healthcare Research Network, Hazelwood

70124

DelRicht Research, New Orleans

70471

DelRicht Research - Mandeville, Mandeville

70817

DelRicht Research - Prairieville, Prairieville

73013

Conrad Clinical Research, Edmond

74133

DelRicht Research - Tulsa, Tulsa

75075

Clinical Investigations of Texas, Plano

75230

Zenos Clinical Research, Dallas

77036

Synergy Groups Medical, LLC, Houston

77061

Synergy Groups Medical, LLC, Houston

78229

Diagnostic Research Group, San Antonio

84107

Wasatch Clinical Research, LLC, Salt Lake City

85712

Tucson Orthopaedic Institute, Tucson

87102

Albuquerque Clinical Trials, Albuquerque

90703

Core Healthcare Research, Cerritos

91360

Millennium Clinical Trials, LLC, Thousand Oaks

91767

Dream Team Clinical Research, Pomona

91942

BioSolutions Clinical Research Center, La Mesa

92103

Artemis Institute for Clinical Research, San Diego

92860

Infinity Clinical Research, Norco

97978

Encompass Clinical Research, Spring Valley

01803

Skylight Health Research, Burlington

Sponsors
All Listed Sponsors
collaborator

NBCD A/S

INDUSTRY

lead

Biosplice Therapeutics, Inc.

INDUSTRY

NCT05603754 - A Study Utilizing Patient-Reported Outcomes to Evaluate the Safety and Efficacy of Lorecivivint (SM04690) for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthritis (STRIDES) | Biotech Hunter | Biotech Hunter