NCT05603312View on ClinicalTrials.gov

A Double-blind Study to Evaluate the Safety of Glutamic Acid Decarboxylase Gene Transfer in Parkinson's Participants

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

October 5, 2022

Primary Completion Date

September 6, 2024

Study Completion Date

September 6, 2024

Conditions
Parkinson's Disease
Interventions
GENETIC

AAV-GAD Low Dose

Bilateral infusion of AAV-GAD low dose

GENETIC

AAV-GAD High Dose

Bilateral infusion of AAV-GAD high dose

PROCEDURE

Sham Surgery

Sham infusion

Trial Locations (6)

10021

Weill Cornell Medicine, New York

10032

Columbia University Irving Medical Center, New York

19107

Thomas Jefferson University, Philadelphia

26506

West Virginia University, Morgantown

48322

Henry Ford West Bloomfield Hospital, West Bloomfield

06510

Yale University - Yale New Haven Hospital, New Haven

Sponsors

Lead Sponsor

MeiraGTx, LLC
All Listed Sponsors
lead

MeiraGTx, LLC

INDUSTRY