Fluoride in Saliva After Use of Fluoride Toothpastes Followed by Fluoride Mouthrinses

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

March 23, 2023

Primary Completion Date

November 4, 2024

Study Completion Date

February 28, 2025

Conditions
Dental Caries
Interventions
DRUG

Crest Cavity Protection toothpaste

Participants will brush their teeth with Crest Cavity Protection toothpaste (1,100 ppm F) for 1 minute, expectorate the foam, and rinse their mouths with 10 mL of tap water for 10 seconds

DRUG

Crest Cavity Protection toothpaste followed by Act Mint Fluoride Rinse

Participants will brush their teeth with Crest Cavity Protection toothpaste (1,100 ppm F) for 1 minute, expectorate the foam, and rinse their mouths with 10 mL of Act Mint Fluoride Rinse (226 ppm) for 1 minute

DRUG

Colgate PreviDent 5000+ toothpaste

Participants will brush their teeth with Colgate PreviDent 5000+ (5,000 ppm F) for 1 minute, expectorate the foam, and rinse their mouths with 10 mL of tap water for 10 seconds

DRUG

Colgate PreviDent 5000+ toothpaste followed by Act Mint Fluoride Rinse

Participants will brush their teeth with Colgate PreviDent 5000+ (5,000 ppm F) for 1 minute, expectorate the foam, and rinse their mouths with 10 mL of Act Mint Fluoride Rinse (226 ppm) for 1 minute

Trial Locations (1)

48109

School of Dentistry, University of Michigan, Ann Arbor

All Listed Sponsors
lead

University of Michigan

OTHER