NCT05598177View on ClinicalTrials.gov

Effect of Dexmedetomidine Preconditioning on Myocardial Ischemia-reperfusion Injury in Patients Undergoing Open Heart Surgery With Cardiopulmonary Bypass

PHASE4CompletedINTERVENTIONAL
Enrollment

64

Participants

Timeline

Start Date

September 1, 2022

Primary Completion Date

May 30, 2023

Study Completion Date

December 31, 2023

Conditions
Ischemia-Reperfusion Injury
Interventions
DRUG

dexmedetomidine

The participant will pump dexmedetomidine at the rate of 1μg/(Kg·h) for 10 minutes at the beginning of anesthesia induction, and then maintain the pump at a rate of 0.5μg/(Kg·h) during the operation.

DRUG

Placebo

The participant will pump saline without dexmedetomidine at the same speed as group D.

Trial Locations (1)

226000

Affiliated Hospital Nantong University, Nantong

All Listed Sponsors
lead

Affiliated Hospital of Nantong University

OTHER