Evaluation of Efficacy and Safety of Rituximab in Patients With Progressive Interstitial Lung Disease (ILD) With Inflammatory Component: a Multicentre Double-blind Placebo-controlled Randomized Trial

PHASE3RecruitingINTERVENTIONAL
Enrollment

126

Participants

Timeline

Start Date

January 16, 2023

Primary Completion Date

July 16, 2026

Study Completion Date

July 16, 2026

Conditions
Lung Diseases
Interventions
DRUG

Rituximab

One course of IV rituximab consisting of a first infusion of 1000 mg (500 mL solution) rituximab (day 1), and a second infusion of 1000 mg (500 mL solution) rituximab two weeks later (day 15)

OTHER

Placebo

One course of IV placebo of rituximab consisting of a first infusion of 500 mL of saline (0.9% sodium chloride) infusion (day 1), and a second infusion of 500 mL of saline infusion two weeks later (day 15)

Trial Locations (1)

Unknown

RECRUITING

Chru Tours, Tours

All Listed Sponsors
lead

University Hospital, Tours

OTHER