Icaritin Soft Capsule Versus Huachansu Tablet in the First-line Treatment of Unresectable Hepatocellular Carcinoma With Poor Conditions and Biomarker Enrichment (Biomarker Enrichment Study of Poor Prognosis HCC Patients, BESTPOP)

PHASE3RecruitingINTERVENTIONAL
Enrollment

261

Participants

Timeline

Start Date

December 12, 2022

Primary Completion Date

August 30, 2025

Study Completion Date

August 30, 2025

Conditions
Hepatocellular Carcinoma
Interventions
DRUG

Icaritin

600 mg (6 x 100 mg capsules) icaritin administered orally twice daily (30 minutes after breakfast and dinner, respectively) until treatment discontinuation criteria are met.

DRUG

Huachansu

1200 mg (4 x 300 mg tablets) huachansu administered orally three times a day (30 minutes after breakfast, lunch and dinner, respectively) until treatment discontinuation criteria are met.

Trial Locations (3)

300060

NOT_YET_RECRUITING

Tianjin Medical University Cancer Institute & Hospital, Tianjin

330006

RECRUITING

The Second Affiliated Hospital of Nanchang University, Nanchang

Unknown

RECRUITING

Chifeng Municipal Hospital, Chifeng

All Listed Sponsors
lead

Beijing Shenogen Biomedical Co., Ltd

INDUSTRY

NCT05594927 - Icaritin Soft Capsule Versus Huachansu Tablet in the First-line Treatment of Unresectable Hepatocellular Carcinoma With Poor Conditions and Biomarker Enrichment (Biomarker Enrichment Study of Poor Prognosis HCC Patients, BESTPOP) | Biotech Hunter | Biotech Hunter