75
Participants
Start Date
August 25, 2023
Primary Completion Date
September 1, 2026
Study Completion Date
December 31, 2026
Eplerenone
After the Pre-Treatment Assessment, participants in the eplerenone arm will be given 50 mg eplerenone. At 2 weeks, eplerenone will be increased to 100 mg.
Chlorthalidone
After the Pre-Treatment Assessment, participants in the chlorthalidone arm will be given 12.5 mg chlorthalidone + 10 mEq potassium. At 2 weeks, chlorthalidone will be increased to 25 mg + 20 mEq potassium.
Potassium
After the Pre-Treatment Assessment, participants in the chlorthalidone arm will be given 12.5 mg chlorthalidone + 10 mEq potassium. At 2 weeks, chlorthalidone will be increased to 25 mg + 20 mEq potassium.
RECRUITING
Brigham and Women's Hospital, Boston
Brigham and Women's Hospital
OTHER