Safety and Effectiveness of the Genio® bilAteral Stimulation for Treatment of Complete Concentric CollapsE and OSA.

NAActive, not recruitingINTERVENTIONAL
Enrollment

124

Participants

Timeline

Start Date

December 28, 2022

Primary Completion Date

September 30, 2026

Study Completion Date

September 30, 2028

Conditions
Sleep Apnea, Obstructive
Interventions
DEVICE

Genio System

The Genio® IS electrode placement does not require an extensive surgical manipulation of the hypoglossal nerve, it requires only a single incision site and does not require battery replacements as those are external components. Whereas UPPP surgery and other similar upper airway enlargement surgeries are much more extensive, are irreversible and tend to have more complications and modest long-term results in reducing OSA severity and symptoms. In summary, the solution offered by the Genio System to treat OSA patients with CCC using bilateral HGNS has a favorable risk-benefit ratio, as demonstrated by evidence from 2 studies.

Trial Locations (16)

14627

University of Rochester, Rochester

19104

Hospital of the University Pennsylvania, Philadelphia

19107

Thomas Jefferson University Department of Otolaryngology, Philadelphia

23507

Eastern Virginia Medical School, Norfolk

29201

Bogan Sleep Consultants, LLC, Columbia

33136

University of Miami, Miami

33176

PharmaDev Clinical Research Institute,, Miami

33487

ENT and Allergy Associates of Florida, LLC, Boca Raton

33620

University of South Florida, Tampa

37232

Vanderbilt University Medical Center, Nashville

46032

Center for ENT and Allergy, PC Ascension Medical Group, Carmel

52242

University of Iowa Institute for Clinical & Translational Science, Iowa City

66160

University of Kansas, Kansas City

75390

University of Texas Southwestern Medical Center, Dallas

80923

Colorado ENT & Allergy, Colorado Springs

02114

Massachusetts Eye & Ear, Boston

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Nyxoah Inc.

INDUSTRY

lead

Nyxoah S.A.

INDUSTRY

NCT05592002 - Safety and Effectiveness of the Genio® bilAteral Stimulation for Treatment of Complete Concentric CollapsE and OSA. | Biotech Hunter | Biotech Hunter