A Safety, Reactogenicity, and Immunogenicity Study of mRNA-1045 (Influenza and Respiratory Syncytial Virus [RSV]) or mRNA-1230 (Influenza, RSV, and Severe Acute Respiratory Syndrome Coronavirus 2 [SARS-CoV-2]) Vaccine in Adults 50 to 75 Years Old

PHASE1CompletedINTERVENTIONAL
Enrollment

392

Participants

Timeline

Start Date

October 14, 2022

Primary Completion Date

February 28, 2024

Study Completion Date

February 28, 2024

Conditions
SARS-CoV-2InfluenzaRSV
Interventions
BIOLOGICAL

mRNA-1010

Sterile liquid for injection

BIOLOGICAL

mRNA-1345

Sterile liquid for injection

BIOLOGICAL

mRNA-1273.214

Sterile liquid for injection

BIOLOGICAL

mRNA-1045

Formulation for injection

BIOLOGICAL

mRNA-1230

Formulation for injection

Trial Locations (30)

2148

Paratus Clinical Research Western Sydney, Blacktown

2259

Paratus Clinical Kanwal, Kanwal

3124

Emeritus Research, Camberwell

4006

Nucleus Network Brisbane Clinic - Centre For Clinical Studies, Herston

4010

Paratus Clinical Research Brisbane, Albion

4101

University of the Sunshine Coast, South Brisbane

28403

Trial Management Associates, Wilmington

28557

Lucas Research, Inc. (Diabetes & Endocrinology Consultants PC), Morehead City

29572

Trial Management Associates, Myrtle Beach

29621

Velocity Clinical Research, Anderson

30030

Cenexel IRA (iResearch Atlanta), Decatur

30331

Atlanta Center for Medical Research - Family Medicine, Atlanta

31904

Centricity Research, Columbus

32720

Accel Research Sites, DeLand

33024

Research Centers of America (cenexel), Hollywood

33709

Accel Research Sites, St. Petersburg

48076

DM Clinical Research, Southfield

61614

Optimal Research, Peoria

77081

DM Clinical Research, Houston

77478

DM Clinical Research, Sugar Land

QLD 4068

AusTrials Taringa, Taringa

NE2 4HH

Newcastle University - Institute of Cellular Medicine (ICM), Newcastle

NG7 2UH

Nottingham University Hospitals NHS Trust - Queen's Medical Centre (QMC) Campus, Nottingham

OX3 7LJ

University of Oxford, Oxford

BS2 8BJ

Bristol Royal Hospital for Children, Bristol

EX25DW

Royal Devon & Exeter Hospital, Exeter

SW10 9NH

Chelsea and Westminster Hospital, London

SW17 0RE

St George's Healthcare NHS Trust - University of London - Th, London

WC1N 3GB

National Hospital for Neurology and Neurosurgery, London

SO16 6YD

Southampton General Hospital, Southampton

All Listed Sponsors
lead

ModernaTX, Inc.

INDUSTRY