Study of the Safety and Neuroprotective Capacity of Scp776 in Acute Ischemic Stroke

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

October 19, 2022

Primary Completion Date

October 31, 2025

Study Completion Date

January 31, 2026

Conditions
Acute Ischemic Stroke (AIS)
Interventions
DRUG

Placebo

Volume Matched Placebo

DRUG

scp776 (1.9 mg/kg)

"Cohort 1 dose regimen:~Intravenous (IV) slow injection(s) over 2 minutes~\- 1.9 mg/kg"

DRUG

scp776 (3.8 mg/kg)

"Cohort 2 dose regimen:~Intravenous (IV) slow injection(s) over 2 minutes~\- 3.8 mg/kg"

DRUG

scp776 (4.8 mg/kg)

Cohort 3 dose regimen: Intravenous (IV) slow injection(s) over 2 minutes - 4.8 mg/kg

DRUG

scp776 (all dose levels)

A composite group encompassing all participants who received any dose level of the investigational drug under evaluation.

Trial Locations (22)

10075

Lennox Hill Hospital, New York

11030

Northshore University Hospital, Manhasset

17033

Penn State Health - M.S. Hershey Medical Center, Hershey

19001

Jefferson Abington Hospital, Abington

30912

Augusta University Medical Center, Augusta

33136

University of Miami - Jackson Memorial Hospital, Miami

33486

Marcus Neuroscience Institute, Boca Raton

43210

The Ohio State University, Columbus

43608

Mercy Health - St Vincent Medical Center, Toledo

44504

Mercy Health - St Elizabeth Youngstown Hospital, Youngstown

45219

University of Cincinnati, Cincinnati

53226

Medical College of Wisconsin and Froedtert Hospital, Milwaukee

63044

SSM Health DePaul Hospital, Bridgeton

64111

St. Luke's Hospital of Kansas City, Kansas City

77030

Houston Methodist Neurological Institute, Houston

85251

HonorHealth Scottsdale Osborn Medical Center, Scottsdale

85719

Banner University Medical Center /Univ of Arizona, Tucson

87106

UNM Hospital, Albuquerque

97213

Providence Portland Medical Center, Portland

97225

Providence St. Vincent Medical Center, West Haven-Sylvan

97239

Oregon Stroke Center at OHSU, Portland

06106

Hartford Hospital, Hartford

Sponsors
All Listed Sponsors
lead

Silver Creek Pharmaceuticals

INDUSTRY

NCT05585606 - Study of the Safety and Neuroprotective Capacity of Scp776 in Acute Ischemic Stroke | Biotech Hunter | Biotech Hunter