Behavioral Change Following Alzheimer's Disease (AD) Biomarker Disclosure

NAEnrolling by invitationINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

February 20, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

May 31, 2026

Conditions
Mild Cognitive ImpairmentAlzheimer DiseaseAmnestic Mild Cognitive Disorder
Interventions
BEHAVIORAL

Diagnostic Disclosure Protocol

Personalized disclosure on cognitive test results and research diagnosis, plus post-disclosure dementia risk reduction counseling.

BEHAVIORAL

Biomarker Disclosure Protocol

Participants receive information about their cognitive test results and research diagnosis just like in the diagnostic disclosure protocol. In addition, participants receive information about whether they currently have elevated or not-elevated amyloid and/or tau based on recent PET imaging. PET is a type of imaging biomarker (Aß-PET and tau PET) for clinical diagnosis of Alzheimer's disease. These actions are followed by post-disclosure dementia risk reduction counseling.

Trial Locations (1)

48109

The University of Michigan, Ann Arbor

All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

lead

University of Michigan

OTHER