200
Participants
Start Date
January 31, 2026
Primary Completion Date
October 31, 2026
Study Completion Date
December 31, 2026
Bupivacaine alone OR Bupivacaine-Ketorolac-Ketamine (BKK) Combination
The plan will be to stratify patients in two groups: intervention group receiving 20 cc combination of BKK (Bupivacaine HCl 60 mg \[3 mg/mL\], Ketorolac Tromethamine 24 mg \[1.2mg/mL\], Ketamine HCl 24 mg \[1.2 mg/mL\]) vs the control group receiving 20 cc of 0.5% bupivacaine (Bupivacaine HCL 100 mg \[5mg/ml\]. The dose can be repeated multiple times during the procedure as per operator's discretion. The patients will be further stratified into sub-groups based on type of procedure they had undergone. Analgesia/anesthesia strategy will be local infiltration of the drug along with a sedating agent based on institutional standard of care. The dose of the medicines will be adjusted as per discretion of the operator to maintain adequate anesthesia/analgesia during and after the procedure.
Kansas City Heart Rhythm Institute, Overland Park
Overland Park Regional Medical Center, Overland Park
Loma Linda University Health, Loma Linda
Cardiac Arrhythmia Service, Loma Linda University Health, Loma Linda, CA
UNKNOWN
Kansas City Heart Rhythm Research Foundation
OTHER