20
Participants
Start Date
October 5, 2022
Primary Completion Date
October 31, 2025
Study Completion Date
October 31, 2025
Bridging radiotherapy (BRT)
RT Part I. The target will be to complete the 9th fraction of radiotherapy (i.e., total of 27Gy) between days -12 and -8 Day -2: BRT Part II (intervention is one fraction 3 Gy to receive a total dose of 3 Gy).
Conditioning chemotherapy
Day -5 to -3: Patients will receive standard of care lymphodepleting chemotherapy
CAR T-cell product
Day 0: Subject will receive standard of care infusion of a manufactured commercial CAR T-cell product.
Memorial Sloan Kettering Cancer Center, New York
Memorial Sloan Kettering Westchester (Limited Protocol Activities), Harrison
Memorial Sloan Kettering Nassau (Limited Protocol Activities), Uniondale
Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities), Commack
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge
Memorial Sloan Kettering Monmouth (Limited Protocol Activities), Middletown
Memorial Sloan Kettering Bergen (Limited Protocol Activities), Montvale
Memorial Sloan Kettering Cancer Center
OTHER