Drug-drug Interaction Study With AZD5305 and Itraconazole in Patients With Advanced Solid Malignancies

PHASE1CompletedINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

November 7, 2022

Primary Completion Date

April 17, 2023

Study Completion Date

May 17, 2024

Conditions
Advanced Solid Malignancies
Interventions
DRUG

AZD5305

"In Part A, the participants will receive a single dose of AZD5305 on Day 1 and Day 7.~In Part B, the participants will receive AZD5305 once daily."

DRUG

Itraconazole

In Part A, the participants will receive Itraconazole twice daily on Day 4 and once daily on Days 5-12

Trial Locations (2)

400015

Research Site, Cluj-Napoca

MD-2025

Research Site, Chisinau

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY