Multi-Center Study of Panosyl-Isomaltooligosaccharides Adjunctive to PPI Therapy to Treat GERD

PHASE2RecruitingINTERVENTIONAL
Enrollment

247

Participants

Timeline

Start Date

March 3, 2023

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2026

Conditions
Gastroesophageal Reflux
Interventions
DRUG

MHS-1031

Study medication will be supplied as a syrup in individual sachets containing 1g (1.5 mL) of MHS-1031. Subjects will be randomized in 2:1 fashion to either study drug (2) or placebo (1)

OTHER

Placebo

Matching placebo is an oral solution formulated to have a degree of sweetness and acidity similar to the study medication and will be provided in equivalent sachets containing 1.5g (1.5 mL) of the oral placebo solution.

Trial Locations (17)

22908

ACTIVE_NOT_RECRUITING

University of Virginia Health System, Charlottesville

22911

COMPLETED

Charlottesville Medical Research Center, Charlottesville

23236

COMPLETED

GI Research Partners, LLC, Richmond

23502

ACTIVE_NOT_RECRUITING

Digestive Disease and Liver Specialists, Norfolk

27612

RECRUITING

M3 Wake Research (CPOR), Raleigh

30328

ACTIVE_NOT_RECRUITING

WR-Mount Vernon Clinical Research (MVCR), Sandy Springs

30345

COMPLETED

EmVenio-Georgia (EMGA), Atlanta

32055

RECRUITING

Wr-Msra, Llc, Lake City

33186

RECRUITING

A Positive Clinical Research, Miami

33407

ACTIVE_NOT_RECRUITING

Health Synergy Clinical Research, West Palm Beach

TERMINATED

West Palm Quality Research (WPQR), West Palm Beach

34684

RECRUITING

Advanced Gastroenterology Associates LLC, Palm Harbor

37232

ACTIVE_NOT_RECRUITING

Vanderbilt University Medical Center, Nashville

49519

RECRUITING

Gastroenterology Associates of Western Michigan PLC (WMCR), Wyoming

75149

RECRUITING

SMS Clinical Research (SMSR), Mesquite

77479

ACTIVE_NOT_RECRUITING

A and U Family Medicine (NCR), Sugar Land

85018

RECRUITING

Elite Clinical Studies LLC, Phoenix

Sponsors
All Listed Sponsors
collaborator

VBHRC Virginia Catalyst

UNKNOWN

lead

Microbiome Health Sciences

INDUSTRY

NCT05556824 - Multi-Center Study of Panosyl-Isomaltooligosaccharides Adjunctive to PPI Therapy to Treat GERD | Biotech Hunter | Biotech Hunter