Ultra-Short Course Bedaquiline, Clofazimine, Pyrazinamide and Delamanid Versus Standard Therapy for Drug-Susceptible TB

PHASE2RecruitingINTERVENTIONAL
Enrollment

156

Participants

Timeline

Start Date

November 24, 2023

Primary Completion Date

August 31, 2025

Study Completion Date

January 31, 2027

Conditions
Tuberculosis, PulmonaryHIV
Interventions
DRUG

Bedaquiline

Daily therapy for 12 weeks

DRUG

Clofazimine

Daily therapy for 12 weeks

DRUG

Pyrazinamide

Daily therapy for 12 weeks

DRUG

Delamanid

Daily therapy for 12 weeks

DRUG

Rifampin

Daily therapy for 26 weeks

DRUG

Isoniazid

Daily therapy for 26 weeks

DRUG

Ethambutol

Daily therapy for 8 weeks

DRUG

Pyrazinamide

Daily therapy for 8 weeks

Trial Locations (2)

Unknown

RECRUITING

GHESKIO, Port-au-Prince

RECRUITING

University of Cape Town, Cape Town

All Listed Sponsors
collaborator

University of Cape Town

OTHER

collaborator

Haitian Group for the Study of Kaposi's Sarcoma and Opportunistic

OTHER

collaborator

University of Stellenbosch

OTHER

collaborator

University of California, Los Angeles

OTHER

collaborator

Harvard School of Public Health (HSPH)

OTHER

lead

Brigham and Women's Hospital

OTHER

NCT05556746 - Ultra-Short Course Bedaquiline, Clofazimine, Pyrazinamide and Delamanid Versus Standard Therapy for Drug-Susceptible TB | Biotech Hunter | Biotech Hunter