Evaluation of Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy

PHASE3CompletedINTERVENTIONAL
Enrollment

1,075

Participants

Timeline

Start Date

October 3, 2022

Primary Completion Date

December 15, 2023

Study Completion Date

December 15, 2023

Conditions
Acute Pain
Interventions
DRUG

SUZ

Tablets for oral administration.

DRUG

HB/APAP

Capsules for oral administration.

DRUG

Placebo (matched to SUZ)

Placebo matched to SUZ for oral administration.

DRUG

Placebo (matched to HB/APAP)

Placebo matched to HB/APAP for oral administration.

Trial Locations (21)

30331

Atlanta Center for Medical Research, Atlanta

33014

Clinical Pharmacology of Miami, Hialeah

33613

ForCare Clinical Research, Tampa

35660

Shoals Medical Trials Inc., Sheffield

45417

Midwest Clinical Research Center, Dayton

67226

Kansas Spine and Specialty Hospital, Wichita

72211

Woodland International Research Group, Little Rock

74037

Center for Orthopaedic Reconstruction and Excellence, Jenks

77598

Houston Physicians Hospital, Webster

78240

Endeavor Clinical Trials, San Antonio

78501

Futuro Clinical Trials, McAllen

84107

JBR Clinical Research, Salt Lake City

85053

Arizona Research Center, Phoenix

91356

New Hope Research Development, Tarzana

91790

New Hope Research Development, West Covina

92103

Pacific Research Network Inc, San Diego

92801

Anaheim Clinical Trials, Anaheim

93301

Trovare Clinical Research, Bakersfield

Texas

"HD Research LLC , First Surgical Hospital"

"HD Research LLC , Legent Orthopedic Hospital"

"HD Research LLC , Houston Heights Hospital"

All Listed Sponsors
lead

Vertex Pharmaceuticals Incorporated

INDUSTRY