Simvastatin Nasal Rinses for the Treatment of COVID-19 Mediated Dysomsia

PHASE1WithdrawnINTERVENTIONAL
0
Timeline

Start Date

May 1, 2023

Primary Completion Date

May 1, 2023

Study Completion Date

May 1, 2023

Conditions
Olfactory DisorderCOVID-19
Interventions
DRUG

Simvastatin

Compounded simvastatin that is suspended within a nasal saline irrigation will be utilized throughout this study. Participants will suspend the contents of the simvastatin capsules (0.1mg, 0.25 mg, 0.5 mg, and 1 mg) into the sinus rinse bottle containing nasal saline. All participants will receive an 8-ounce sinus rinse bottle and a 4-week supply of USP Grade Sodium Chloride \& Sodium Bicarbonate Mixture (pH balanced, Isotonic \& Preservative \& Iodine Free) commercially prepared packets. Participants will either need to purchase distilled water or boil tap water for five minutes for use with the saline irrigation.

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Duke University

OTHER

lead

Washington University School of Medicine

OTHER

NCT05542095 - Simvastatin Nasal Rinses for the Treatment of COVID-19 Mediated Dysomsia | Biotech Hunter | Biotech Hunter