A Study of Melphalan in People With Lymphoma Getting an Autologous Hematopoietic Cell Transplant

PHASE1RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

September 9, 2022

Primary Completion Date

September 30, 2026

Study Completion Date

September 30, 2026

Conditions
LymphomaLymphoma, B-CellLymphoma, T-CellLymphoma, HodgkinLymphoma, Non-Hodgkin
Interventions
OTHER

Pharmacokinetics

Six peripheral blood samples of 5 ml in lithium heparin tubes will be collected at 5, 15, 30, 40, 75, and 150 minutes after the melphalan, for PK testing. The first four time points are +/- 2 min and the last two time points are +/- 5 minutes.

OTHER

Pharmacokinetics

Six peripheral blood samples of 5 ml in lithium heparin tubes will be collected at 5, 15, 30, 40, 75, and 150 minutes after the melphalan to determine the actual AUC achieved using the population PK.

Trial Locations (1)

10065

RECRUITING

Memorial Sloan Kettering Cancer Center, New York

All Listed Sponsors
lead

Memorial Sloan Kettering Cancer Center

OTHER